What is DNA Fragmentation?

Posted & filed under IVF, Sperm, Tests, The Basics, The Journey.

The DNA Fragmentation is one of several elements of semen quality used to assess the male fertility potential. Sperm’s ability to fertilize an egg is dependant on healthy DNA. But some sperm are fragmented. Healthy DNA is arranged in a double-helix spiral bound by cross-bonds resembling a ladder. DNA damage means the bridges become unstable… Read more »

What’s more effective: IUI or FSP?

Posted & filed under Sperm, The Journey.

“My husband and I have unexplained secondary infertility and are about to start our first IUI. I was reading about the success rates of FSP (fallopian sperm perfusion) for unexplained infertility and how FSP may be more effective than IUI. It is suggested that couples with unexplained infertility may benefit from FSP over IUI, resulting in higher… Read more »

Should I have one or two intrauterine inseminations?

Posted & filed under Eggs, Sperm.

If your underlying concern is around serious male factor subfertility, or blocked/compromised tubes (as can happen with endometriosis), or serious concerns around egg quality, then IVF is by far the better choice for achieving pregnancy. Not everybody needs IVF. Many patients may benefit from intrauterine inseminations. IUI, where sperm is washed and placed high within… Read more »

Are there any activities I should do the day of my IUI?

Posted & filed under Sperm, The Basics.

The short answer is – there aren’t. Many corners of the internet encourage people to continue lying on their back, perhaps with a pillow under their bum after intercourse. The speculation is that this allows more sperm access to the womb and increases the chances of pregnancy. Does it work? I don’t know. But, if… Read more »

I’m having IUI, how do I interpret the sperm numbers?

Posted & filed under Sperm, The Basics.

You’ve talked to your fertility provider and decided intrauterine insemination (IUI) is the right choice for you. Great! By this point, we generally have a sperm count. This can be divided into two parts: The initial sample and the washed sample. Initial Sample We like to see sperm in the “normal” range. This is because… Read more »

When is IUI the right choice?

Posted & filed under Eggs, Sperm, The Basics.

Intrauterine insemination (IUI) is a simple “bridge” procedure between natural attempts to conceive at home, and the more technical process of IVF. Intrauterine insemination is kind of like having sexual intercourse timed to when you ovulate. The difference is  that it helps bypass any obstacles sperm may encounter at the cervix. Some examples of when… Read more »

“My sperm morphology results say 75% are abnormal. Help!”

Posted & filed under Sperm, Tests.

25% normal morphology is low. But depending on how your clinic processes samples, morphology can often come out low-normal or low. Something to try: Ask to have the test repeated, along with a DNA fragmentation assay. Consider taking antioxidant vitamins. Speak to a urologist – they’re the final word in sperm. In the end, 25%… Read more »

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